The new coronavirus, affects many organs and tissues in our body. In addition to the lungs, in fact, it also attacks the liver, brain, skin, testicles and heart.
During the pandemic, for example, many studies have shown that numerous patients with Covid-19 have also reported serious damage to the circulatory system. And while the entire scientific community is attempting to find an explanation as to why the virus causes blood clots , a frequent complication of the disease, research has just shown how the blood of the sick could be used to predict disease progression.
The study, published in the journal Cell System, therefore represents an important step forward in the development of a diagnostic test capable of predicting whether a patient will develop severe symptoms. But not only: a research by 23andMe , a company specialized in DNA analysis and in research of correlations between genome and disease risk, found that the blood group plays a role in the susceptibility to Covid-19. According to the results, still preliminary, in fact, the blood group 0 would significantly reduce the risk of contracting the new coronavirus .
But what exactly emerged from these two new studies? According to two recent analyzes, blood could play an important role for Covid-19 and provide useful information for both the susceptibility and the progression of the disease.
In the first article, researchers from the Charité University Hospital in Berlin, in collaboration with the Francis Crick Institute in London, hunted for biomarkers , biological characteristics that could provide a reliable tool for predicting disease progression and severity . Using innovative analytical techniques, in fact, the research team discovered some differences in blood samples from severe cases compared to those with milder symptoms. By analyzing the blood plasma of 31 Covid-19 patients, the researchers were able to determine the levels of various proteins in the blood and identify variousbiomarkers , linked to the severity of their disease.
From the results, in fact, they identified 27 proteins that varied quantitatively according to the severity of the disease. “These results lay the foundation for two very different applications. A possible future use would be for the prognosis of the disease, “explains study author Markus Ralser . “An early blood test would allow the doctor to predict whether or not a Covid-19 patient will develop severe symptoms. This could therefore save lives: the sooner doctors know which patients will need intensive care , the faster they will be able to take advantage of the available treatment options. ”
Another possible future application, adds the expert, could be that of a diagnostic test , which could be more precise and objective regarding a patient’s health conditions. “In some cases, a patient’s symptoms don’t seem to provide an accurate picture of their true state of health,” comments the author. “An objective assessment, based on their biomarker profile, could be extremely helpful in this regard.”
The second study, however, seems to confirm the results of two recent studies carried out in China , Italy and Spain, in which a link between blood group , determined by the ABO gene, and susceptibility and severity of Covid-19 has been highlighted . The Californian company 23andMe, in fact, has suggested how a specific type of blood could play a protective role and make it immune to the coronavirus. To understand this, the researchers reviewed the data of 750,000 participants, discovering a direct link between the patient’s blood group and its susceptibility to infection. In particular, preliminary results showed that participants with blood group 0 have, in general, a lower probability (between 9 and 18%) of being positive for the virus than participants with other blood groups, and those more exposed coronavirus (like healthcare professionals ) 13-26% less than contracting the virus. For now, therefore, preliminary data seem to provide evidence of the importance of a person’s blood group in different susceptibilities to coronavirus.